By Patrick Holford In terms of a cost-benefit ratio, Lecanemab has to be one of the worst in history. Reported in the media this week as a ‘breakthrough Alzheimer's medication’ - is this really the case? On the benefit side those in the drug company’s own trial got statistically...
by Patrick Holford https://vimeo.com/995347099/0868666b39 -- Drugs won’t prevent dementia. Last week’s Lancet Commission on dementia prevention is facing mounting criticism, for favouring targets for drugs including lowering cholesterol and amyloid and completely ignoring...
In a world often filled with daunting health challenges, Alzheimer's Prevention Day stood out as a beacon of hope and action. This year was the first launch of this global initiative and we were privileged to witness an incredible turnout: over 10,000 individuals visited our site, driven by a...
By the Alzheimer’s Prevention Expert Group -- You may have heard of a search for new tests to find those most likely to get Alzheimer’s disease? But is this misdirected? Perhaps so, according to the Alzheimer’s Prevention Expert Group (APEG) - a collaboration of top...
One of the hottest discoveries in brain health is the positive effect of switching the fuel for your brain from sugar to ketones, derived from fat. High-fat, low-carb diets designed to put you in ‘ketosis’, with measurable levels of ketones flowing in your blood- stream and consequently brain,...
TODAY is the first, global Alzheimer’s Prevention Day! An initiative created by a group of world-leading experts on Alzheimer’s prevention have designed a free, online 3-minute Alzheimer’s Prevention Check that helps you see, at a glance, what simple diet and lifestyle changes most help...
Yesterday’s announcement by the Alzheimer’s Society that dementia will cost the UK almost £91bn a year by 2040 highlights why prevention has to be the way forward. (See the Guardian Article here) “Dementia’s devastating impact is colossal – on the lives of those it affects, on the...
Author of the article is Patrick Holford and the Alzheimer’s Prevention Expert Group. The single greatest genetic predictor of Alzheimer’s disease is the presence of the ApoE4 variant of the ApoE gene, carried by about one in five people. Having this contributes 4% to 6% of the absolute...
Written by Jerome Burne, see the original article at the Daily Mail here. Find out about Jerome here. It is over 20 years since I discovered in my fifties that I have a copy of the gene, ApoE4, that’s been linked to a raised risk of Alzheimer’s. -- It is over 20 years since I...
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