What is glutathione?

Glutathione is an antioxidant produced by the body from the amino acid methionine.  Methionine is first of all converted to cysteine and then on to glutathione.  Glutathione has a role to play in the lowering of homocysteine and in the protection of the brain from harmful oxidants.

What is the Glutathione Index?

The Glutathione Index is the ratio of ‘fully-loaded’ glutathione, the body’s most important antioxidant, and ‘spent’ glutathione (GSH/GSSH). The body recycles glutathione through the action of enzymes to ensure a ready supply of ‘fully-loaded’ glutathione. It is the best way to measure the equivalent of your antioxidant potential and is associated with cognitive function and brain ageing.

What is a good Glutathione Index?

A desirable level is above 500.  Below 400 is an indicator that you need to increase your intake of antioxidants from food and/or supplements, and/or reduce your intake of oxidants from smoking, pollution or fried food. 

What do I need to do before taking the test?

Avoid supplements for 24 hours before taking the test, fast for 12 hours and avoid coffee, alcohol and smoking immediately before taking the test.

How can I support my Glutathione Index?

Vitamin B6, found in leafy greens, nuts and seeds, and vitamin B12, found in meat, fish and eggs, are important to include within the diet. Include colourful foods with polyphenols such as olives, blueberries, beetroot, and cherries. Avoid smoking and pollution.

What supplements may help?

Supplements providing glutathione or N-acetylcysteine (NAC), vitamins A, C, E, B3, selenium, zinc, magnesium, coenzyme Q10, lipoic acid, resveratrol, anthocyanins for example in bilberry or black elderberry will support an optimal Glutathione Index.