because prevention is better than cure.

because prevention is better than cure.

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Bilingualism & Cognition (2015)

This study investigated bilingualism & cognition. Study included 28 older adult participants – 14 monolingual participants and 14 bilingual participants (who had been bilingual since before age 11). All participants were subjected to a fMRI and had no diagnosed mental health conditions.

Results indicated:

Bilingual participants performed better on tasks and had better working memory (p<0.01) and better connectivity (p=0.002), compared with the monolingual group (p=0.17)

Results observed for other types of memory were not significant

Study size was small. Further large scale warranted. Study did not specify regarding bilingualism, as to whether participants spoke more than 2 languages, or whether certain type and complexity of language afford greater protection (i.e romance languages, Germanic languages etc.). Further research merited to explore effects of bilingualism on other types of memory.

Abstract available here

Grady, C. L., Luk, G., Craik, F. I., and Bialystok, E. (2015). Brain network activity in monolingual and bilingual older adults. Neuropsychologia 66, 170–181. doi: 10.1016/j.neuropsychologia.2014.10.042

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Socialisation, Education & Cognition (2008)

In this study memory change over 6 years was assessed using a large scale sample (16, 638 elderly individuals born <1948) from Health and Retirement Study. Growth curve models were analysed with reference to memory recall of a 10 word list and levels of social integration (i.e with family, volunteering, marital status).

Results indicated:

Socialisation demonstrated as a predictor of slower memory decline (p<.01). 

In individuals with vascular disease, socialisation observed to be protective buffer ( (p< 0.05)

Memory amongst least socialised deteriorated at twice the rate of other participants, with association greatest amongst those with <12 years of education (p<0.07)

The study indicates that socialisation and levels of education may be protective factors for memory decline. The study also suggests that socialisation may reduce risk for memory decline in individuals with vascular diseases. The study did not use a robust means of measuring memory capability, such as MMSE. Results for socialisation as a predictor of slower memory decline not statistically significant. However, socialisation in individuals with vascular disease as a protective factor was observed to be statistically significant. More research required as to the mechanisms of how socialisation reduces risk of memory decline in vascular disease. Findings for education as a protective factor were observed to be statistically significant. More research required into to what level of education is most protective against memory decline.

Abstract can be viewed here

Ertel, K. A., Glymour, M. M., & Berkman, L. F. (2008). Effects of social integration on preserving memory function in a nationally representative US elderly population. American journal of public health, 98(7), 1215–1220.

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Fasting & Cognitive Performance (2021)

This study explored fasting & cognitive performance. It identified that biological ageing is a process which is accelerated and exacerbated by excessive calories and a sedentary lifestyle. Further, these factors combined may increase the risk of developing neurodegenerative diseases. This systematic review explored the role of different types of IF (intermittent fasting) on cognitive function, with specific focus on BDNF (brain derived neurotrophic factor) as a marker. Reduction of levels of BDNF has been associated with cognitive decline and increased risk of Alzheimer’s disease. Moreover, reductions in BDNF may result in a reduction in synaptic plasticity, memory and learning.

The study accepted and appraised 82 papers. Key findings were:

IF modulated BDNF supporting synaptic maturation and function

Primary evidence demonstrates pro-cognitive and neuroprotective effects of IF and BDNF

Sex specific differences were observed in response to IF

IF was suggested to be supportive for brain health and sustaining cognitive performance into old age, although it was identified further research is required into this area

The abstract is available here:

Seidler, K., & Barrow, M. (2021). Intermittent fasting and cognitive performance – Targeting BDNF as potential strategy to optimise brain health. Frontiers in neuroendocrinology65, 100971. Advance online publication. https://doi.org/10.1016/j.yfrne.2021.100971

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Mediterranean, DASH or MIND Diets (2019)

Results suggest that higher adherence to the Mediterranean, DASH, or MIND diets is associated with less cognitive decline ans well as a lower risk of Alzheimer’s Disease (AD). Evidence for an association with dementia was inconsistent.

The MIND diet may be more protective against cognitive decline and AD than the Mediterranean and DASH diets, based on observational studies. However, more evidence on the MIND diet is required to draw a firm conclusion. Furthermore, the Mediterranean diet seems more protective against AD than the DASH diet.

Based on the studies included in the review, olive oil consumption seems to be an important component underlying these associations.

The full text can be accessed here.

The Mediterranean, Dietary Approaches to Stop Hypertension (DASH), and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diets Are Associated with Less Cognitive Decline and a Lower Risk of Alzheimer’s Disease – A Review. van den Brink, A.C., Brouwer-Brolsma, E.M., Berendsen, A.A.M. et al. (2019). Advanced Nutrition. 10(6), pp1040-1065

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Alcohol, caffeine and cognitive deficits (2021)

The evidence for the relationship between alcohol, coffee and tea and cognitive deficits/benefits
has been confounding to date. This meta-analysis aimed to assess the current evidence
available in terms of the dose–response relationship between alcohol, coffee or tea
consumption and cognitive deficits.
Interestingly, it concluded that, based on the studies and data reviewed, whilst excessive
consumption of alcohol is known to have adverse health effects, light consumption of alcohol
(<11 g/day) and of coffee (<2.8 cups/day) are associated with reduced risk of cognitive deficits.
It also concludes that the cognitive benefits of green tea consumption increase with its daily
consumption.


The full text can be accessed here.

Alcohol, coffee and tea intake and the risk of cognitive deficits: a dose-response meta-analysis. Ran, L.S., Liu, W.H., Fang, Y.Y. et al. (2021) Epidemiology & Psychiatric Sciences. 30 (e13).

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Homocysteine & Alzheimer’s Disease (2002)

A total of 1092 subjects without dementia (667 women and 425 men; average age, 76 years) were followed for an average of 8 years. Their homocysteine levels were monitored and it was noted which of those went onto develop dementia and Alzheimer’s. The authors concluded that an increased level of homocysteine in the blood is a “strong, independent risk factor for the development of dementia and Alzheimer’s Disease”. There was a doubling of risk for Alzheimer’s with a homocysteine level greater than 14mmol/l.

Seshadri S et al,Plasma homocysteine as a risk factor for dementia and Alzheimer’s disease.N Engl J Med., 346(7):476-83, 2002

Click here for the abstract

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Omega 3 & Cognitive Decline (2007)

This study investigated omega 3 & cognitive decline. This was a prospective study of 2,000 people aged 50 to 65 years old. Results indicated that risk of global cognitive decline increased with elevated palmitic acid in both fractions and with high arachidonic acid and low linoleic acid in cholesteryl esters. Higher n-3 HUFAs reduced the risk of decline in verbal fluency, particularly in hypertensive and dyslipidemic subjects.

M A Beydoun, ‘Plasma n-3 fatty acids and the risk of cognitive decline in older adults: the Atherosclerosis Risk in Communities Study’, Am J Clin Nutr., vol 85(4):1103-1111, 2007

Click here for the abstract

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Fish Oil & Cognitive Decline (2007)

This study investigated fish oil & cognitive decline. 210 men aged 70 to 89 years old were followed for 5 years. There was a significant association between intake of fish oil (EPA and DHA) from diet and rate of cognitive decline, with those taking in the most fish oil from oily fish showing the least decline. The measure of decline used the Mini-Mental State Exam (MMSE) which includes questions on orientation to time and place, registration, attention and calculation, recall, language, and visual construction.

B M van Gelder et al, ‘Fish consumption, n-3 fatty acids, and subsequent 5-y cognitive decline in elderly men: the Zutphen Elderly Study’ American Journal of Clinical Nutrition, vol (85)4; 1142-1147, 2007

Click here for the abstract

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Calcium & Cognitive Decline (2007)

A total of 4,500 elderly people were involved in a 5-11 year study of the effects of blood calcium levels on cognitive decline. Cognitive function was measured using the Mini-Mental State Examination (MMSE) and other measures of attention and memory. Higher levels of blood calcium (but still within the normal levels) was associated with worse cognitive function at the beginning of the study. They were also associated with a faster rate of decline in cognitive function during follow-up.

Schram MT et al, ‘Serum calcium and cognitive function in old age’, J Am Geriatr Soc. 2007 Nov;55(11):1786-92

Click here for the abstract

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Cognitive Performance & Fish Intake (2007)

This study examined the relationship between cognitive performance & fish intake. The study included 2,031 elderly Norwegians. The researchers report those eating at least 10 grams of fish a day performed significantly better in tests for cognitive performance, compared with people who ate less than 10 grams of fish and fish products. The best test scores occurred in those who consumed the most fish and fish products, which equates to 75 grams per day. Positive effects were observed to be more pronounced in unprocessed fish compared with processed fish intake. Interestingly, there was no significant difference between the consumption of lean or fatty fish, suggesting that the effects were due to something other than omega-3 fatty acids. However, further research is required to explore this area further.

Click here for the abstract

Nurk E et al., ‘Cognitive performance among the elderly and dietary fish intake: the Hordaland Health Study’, Am J Clin Nutr. 2007 Nov;86(5):1470-8

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