A recent study of 1,178 women found that those carrying the APOE4 gene taking Hormone Replacement Therapy (HRT) had a better delayed memory score compared to APOE4 carriers that were not taking HRT, and to non-APOE4 carriers.[1] They also had slightly larger brain volumes in certain areas. This...
By Patrick Holford Does what you eat affect your risk for dementia later in life and, if so, what is the best diet to protect your brain and prevent cognitive decline? Many studies have been published with different results ranging from no effect at all, as reported in a study in Sweden[i], to...
By Patrick Holford Brain shrinkage left, normal brain right Why Dementia rates are higher in the west In some countries, for example India and China, that proportion appears to be less than half that occurring in Britain. When people in one country suffer much more from a disease than...
By Patrick Holford A global conference of leading world experts in dementia prevention has today identified four easy ways that could reduce risk of dementia by half and eight that could cut your risk by two thirds. The research was shared, for the first time, at the Alzheimer’s...
By Patrick Holford After 40 failed trials for drugs injecting anti-amyloid antibodies (AAAs) one, Lecanemab[i], has finally shown a modest benefit on cognitive function in those with early-stage Alzheimer’s. But they come with a terrible cost - adverse effects that include brain swelling and...
Watch this film – fuel your brain with fat or slow carbs for better energy https://player.vimeo.com/video/736984708?h=dc5bdd05d9&badge=0&autopause=0&player_id=0&app_id=58479 All cells in the body can burn either sugar for energy, or fatty acids, derived from fat. That fat...
Life is a balancing act between making energy by combusting glucose with oxygen, then generating ‘oxidant’ exhaust fumes, and disarming them. In the end, we lose, which is why all oxygen-based life forms have a finite life – and why your brain ages. However, you can not only add years to...
A person’s emotional health, reflected in levels of anxiety, depression, lack of purposeful activities, positive attitude and social interaction, as well as sleep, are associated with increased future risk of cognitive impairment and dementia. Those reporting anxiety have a 35% higher...
B vitamins are essential for many aspects of brain function. They are essential for healthy methylation, which is needed to build brain cell membranes and neurotransmitters that pass messages between brain cells. Hence B vitamins, especially B6, B12 and folate, are essential for the brain’s...
